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The effects of freezing human dentin and cementum before implantation in the subcutaneous tissues of the rat
Author(s) -
Morris M. L.
Publication year - 1969
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1969.tb01981.x
Subject(s) - cementum , bone decalcification , dentin , connective tissue , resorption , chemistry , dentistry , anatomy , pathology , biology , medicine
Twenty‐two sections of human roots including cementum and dentin were preserved by freezing at ‐5 degrees centigrade for an average of 27 days and then implanted into the subcutaneous tissues of the rat for periods up to one year. The reactions of the host connective tissues were compared with those previously noted around implants from freshly extracted teeth. Freezing caused quantitative rather than qualitative differences. Tissue reactions were seen earlier and to a greater degree than with fresh implants. It was concluded that freezing is a suitable method for preserving roots to be used for experimental heteroptic implantation in rats. The results also suggested that root resorption may consist of alternate decalcification and cellular digestion.