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The effect of deficiencies of calcium, vitamin D or calcium and vitamin D and of variations in the source of dietary protein on the supporting tissues of the rat molar
Author(s) -
Oliver W. M.
Publication year - 1969
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1969.tb01946.x
Subject(s) - calcium , cementum , medicine , endocrinology , osteoporosis , chemistry , osteomalacia , vitamin d and neurology , dental alveolus , periodontal fiber , osteoid , molar , vitamin , rickets , demineralization , dentistry , enamel paint , dentin
An histological investigation has been carried out on the periodontal tissues of young rats fed for eight weeks on diets deficient either in calcium (calcium content 0.026 per cent; calcium to phosphorus ratio 0.058), vitamin D, or calcium and vitamin D, in which protein was supplied either as blood albumen or egg albumen. When the diet contained blood albumen, the deficiency of calcium resulted in alveolar changes resembling osteoporosis and in a reduction in the number and diameter of the fibres of the periodontal ligament. When the diet contained blood albumen, the deficiency of calcium and vitamin D caused alveolar changes resembling osteoporosis and a reduction in the number and diameter of the fibres of the periodontal ligament. The deficiency of vitamin D had no obvious effect on the periodontal tissues of the rat. The substitution of egg albumen for the blood albumen in the diets intensified the osteoporotic changes caused by the deffciency of calcium. In rats deficient in calcium and vitamin D it superimposed an osteomalacic change, resulting in a condition of the alveolar process which resembled a combination of osteomalacia and osteoporosis. It also increased the incidence of areas of resorption of primary cementum in all dietary groups. The cementoid on the surface of secondary cementum behaved under these conditions of dietary stress in the same way as the osteoid. The manner in which the dietary deficiencies may produce these changes is discussed.