Changes in vascular proliferation after local application of sex hormones

The effect of locally applied female sex hormones ‐ Gonadex®, Ovex‐B®, Stilbol®, and Progesteron® ‐ on the second phase of inflammation, vascular proliferation, has been explored by micro‐angiography of the micro‐vascular architecture of the rabbit's ear. The estrogens and progesterone stimulated vascular proliferation at the site of a primary micro‐trauma (the injection). Chorionic gonadotropin, however, did not induce any recognizable micro‐vascular proliferation. These findings are discussed in the light of present knowledge of hormonal influence on the gingival tissues.