Premium
Effects of local cartilage applications on gingival wound healing in rats
Author(s) -
Stahl S. Sigmund
Publication year - 1966
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1966.tb01855.x
Subject(s) - foundation (evidence) , medicine , dentistry , oral surgery , library science , political science , law , computer science
Twenty‐five young adult Sprague‐Dawley rats were injured at the gingiva mesial to the maxillary left and right first molars. The injury at the left first molar received daily applications of cartilage microparticles for five days following wounding. The right wound site served as the untreated control. Animals were sacrificed at varying time intervals over a twenty‐eight days experimental period and the maxillae were prepared for histologic study. Cartilage treated wounds showed an initial increase in cellular activity and a subsequent delay in connective tissue maturation. Crestal oste‐ogenesis appeared to be delayed in the cartilage treated areas. The presence of cartilage micro‐particles did not affect the apical migration of the epithelial attachment which followed gingival injury.