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Dietary modulation of the inflammatory cascade
Author(s) -
Dawson Dolphus R.,
BranchMays Grishondra,
Gonzalez Octavio A.,
Ebersole Jeffrey L.
Publication year - 2014
Publication title -
periodontology 2000
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.725
H-Index - 122
eISSN - 1600-0757
pISSN - 0906-6713
DOI - 10.1111/j.1600-0757.2012.00458.x
Subject(s) - medicine , rheumatoid arthritis , inflammation , immune system , immune modulation , periodontitis , arthritis , immunology , bioinformatics , biology
Dietary supplementation has traditionally consisted of adding vitamins and/or minerals to correct or prevent a nutritional deficiency. When supplementing the diet with other inflammatory mediators, such as essential fatty acids, there is an adjunctive benefit to the standard therapies used in the control of chronic inflammatory diseases such as Crohn’s disease or rheumatoid arthritis. This review focuses on the strategies utilized for therapeutic modulation of the inflammatory cascade through dietary supplementation with specific biomolecules. Examples of how these biomolecules affect local and systemic immune responses to chronic inflammation are examined. In particular, an overview of the literature identifying the potential to modify the host response to chronic periodontitis is provided.