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Do X‐linked diseases affect periodontal health?
Author(s) -
Chien HuaHong,
Hart Thomas C.
Publication year - 2013
Publication title -
periodontology 2000
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.725
H-Index - 122
eISSN - 1600-0757
pISSN - 0906-6713
DOI - 10.1111/j.1600-0757.2012.00441.x
Subject(s) - gingivitis , medicine , periodontitis , etiology , aggressive periodontitis , affect (linguistics) , periodontal disease , genetic syndromes , genetics , bioinformatics , dentistry , pathology , biology , pediatrics , linguistics , philosophy
Genetic factors play an important etiologic role in destructive periodontal diseases. There have been reports that sex chromosomes, especially disorders associated with the X chromosome, affect periodontal health. Although numerous X‐linked diseases have been reported to be associated with various periodontal diseases, the association of gingivitis and/or periodontitis with these genetic syndromes should be considered tenuous and raises the question of whether the periodontal manifestation truly arises from an underlying X‐linked genetic etiology. A brief overview of genetics in relation to sex chromosomes and putative X‐linked genetic periodontal diseases is given.