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Salivary IgA responses to bacteria in dental plaque as related to periodontal and HIV infection status
Author(s) -
Myint Maung Maung,
Steinsvoll Svein,
Odden Kåre,
Dobloug Jan,
Schenck Karl
Publication year - 1997
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1997.tb00218.x
Subject(s) - saliva , prevotella intermedia , actinobacillus , fusobacterium nucleatum , gingivitis , streptococcus mutans , medicine , periodontitis , porphyromonas gingivalis , immunology , dental plaque , human immunodeficiency virus (hiv) , chronic periodontitis , microbiology and biotechnology , biology , dentistry , bacteria , genetics
Levels of total IgA and specific IgA reactive with Streptococcus mutans, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens and Fusobacterium nucleatum were measured by ELISA in parotid saliva from HIV + and HIV − persons with healthy gingiva (HG), chronic gingivitis, chronic marginal periodontitis (CMP), or neerotizing ulcerative periodontitis (NUP). When the HIV+ group was compared with the HIV − group regardless of periodontal status, total salivary IgA concentration was higher in HTV + patients, but no such difference was observed for total IgA output. HIV + CMP displayed higher total IgA concentration as compared with HIV − CMP. No significant differences in specific IgA outputs and ratios were detected between HTV + and HIV − subgroups with similar periodontal status. HIV − NUP displayed increased specific IgA output towards S. mutans and increased specific IgA ratio values towards S. mutans, P. gingivalis and P. nigrescens as compared with HIV + CMP, and increased specific IgA ratio values towards S. mutans and P. nigrescens as compared with HIV + HG. No such differences were observed between the HIV − subgroups. In sum. salivary IgA responses to bacteria in dental plaque seem not to be related to chronic periodontal disease and HIV infection, but are possibly influenced by acute periodontal infection.