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Effect of xylitol‐containing chewing gum on sorbitol metabolism in dental plaque
Author(s) -
Assev Synnøve,
Rølla Gunnar
Publication year - 1995
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1995.tb00125.x
Subject(s) - xylitol , sorbitol , dental plaque , sucrose , chewing gum , chemistry , food science , dentistry , medicine , fermentation
The aim of the present study was to examine whether a long‐term use of chewing gum with xylitol as the only sweetener would affect sorbitol metabolism in dental plaque. Ten test subjects used xylitol‐sweetened chewing gum for 12 weeks. Plaque was collected at three occasions; 1) Control plaque; 2) Test plaque I: plaque collected after 12 weeks of chewing xylitol‐containing chewing gum; 3) Test plaque II: sucrose‐stimulated plaque collected 2 d after Test plaque I was collected. Plaque suspensions were incubated with [ 14 C]sorbitol, and uptake of sorbitol and production of sorbitol metabolites were determined by HPLC. Plaque formation and sorbitol uptake were significantly reduced.