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Susceptibility of Streptococcus mutans and Streptococcus sobrinus to antimicrobial agents after short‐term oral chlorhexidine treatments
Author(s) -
Järvinen Helinä,
Pienihäkkinen Kaisu,
Huovinen Pentti,
Tenovuo Jorma
Publication year - 1995
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1995.tb00007.x
Subject(s) - streptococcus sobrinus , streptococcus mutans , chlorhexidine , microbiology and biotechnology , antimicrobial , penicillin , antibiotics , minimum inhibitory concentration , chemistry , medicine , dentistry , biology , bacteria , genetics
Effects of three different types of short‐term applications (1–3 limes during 1 week) of chlorhexidine (1 or 40%) on the susceptibility of 863 clinical isolates of Streptococcus mutans and 53 isolates of Streptococcus sobrinus from 58 subjects were studied. Chlorhexidine‐resistant isolates were not found either before or after the treatment. The minimum inhibitory concentrations (MICs) to chlorhexidine of all isolates of S. mutans were ≤1 μg/ml, and of S. sobrinus ≤2 μg/ ml. S. mutans and S. sobrinus were also susceptible to ampicillin, penicillin, cefuroxime, and tetracycline. In conclusion, different short‐term chlorhexidine regimens do not induce resistance in S. mutans or S. sobrinus and, furthermore, these species have so far retained their susceptibility to common antibiotics.