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Protein composition, adhesion, and agglutination properties of saliva in burning mouth syndrome
Author(s) -
TammialaSalonen Tuulikki,
Söderling Eva
Publication year - 1993
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1993.tb01107.x
Subject(s) - saliva , agglutination (biology) , sialic acid , chemistry , mucin , medicine , immunology , biochemistry , antibody
Resting and stimulated whole saliva and parotid saliva of men and pre‐ and post‐menopausal women with burning mouth syndrome (BMS) and their matched controls were studied. Women with BMS had slightly, but not significantly, higher flow rates than their controls. The total protsein concentration in stimulated saliva of women with BMS was significantly lower than that of controls. This difference was not associated with the flow rate. The proportional amount of sialic acid, used as an indicator of mucin concentration, was higher in subjects with BMS than in their controls. SDS‐PAGE showed no consistent differences in the protein profiles of saliva, nor were any differences observed in the adhesion or agglutination assays between subjects with BMS and their matched controls. Thus, the present results indicate that BMS is not associated with a decrease in the protecting and lubricating properties of saliva.