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Contribution of autogeneic membranous bone chips and bone paste to healing of rabbit skull defects
Author(s) -
Isaksson Sten,
Alberius Per,
Klinge Björn,
Jönsson Jörgen
Publication year - 1992
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1992.tb01070.x
Subject(s) - trephine , skull , rabbit (cipher) , dentistry , bone healing , inlay , medicine , bone tissue , biomedical engineering , anatomy , surgery , statistics , mathematics
In skeletal surgery, bone chips and bone paste are often used to facilitate bony repair. However, no comparative investigation between these forms of bone graft implantation has been undertaken. In this study four trephine skull defects were produced in each of 14 adult rabbits and inlays of bone paste and two separate amounts of bone chips were then implanted in each animal. The results were compared relative to a control defect and assessed by gross inspection, light microscopy, and contact radiography after periods of 4 and 15 wk. Bone chips offered only minor advantages over controls in the defects investigated and differences in bony regeneration between the diversified amounts of bone chips were negligible. After bone paste implantation, a cellular and mature bone was rapidly produced. The clinical significance of these findings is discussed.