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Comparative antibacterial effects of chlorhexidine and stannous fluoride‐amine fluoride containing dental gels against salivary mutans streptococci
Author(s) -
OSTELA ILKKA,
KARHUVAARA LAURA,
TENOVUO JORMA
Publication year - 1991
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1991.tb01044.x
Subject(s) - saliva , streptococcus mutans , dentistry , chlorhexidine , fluoride , microbiology and biotechnology , chemistry , placebo , medicine , bacteria , biology , inorganic chemistry , genetics , alternative medicine , pathology
— Forty‐five young adults were divided into three groups of equal size and given a professional toothcleaning (3 times during 1 wk) with dental gels containing either chlorhexidine (CHX, 1%), or a SnF 2 ‐amine fluoride (AmF) combination (F − content 1.20%). The control group received toothcleaning with a placebo gel. The study was done double blind. The number of salivary mutans streptococci was monitored for 11 wk after the gel treatment using both mitis‐salivarius‐bacitracin agar plates and the chairside method based on the adhesion of mutans streptococci on plastic strips (DentocuIt‐SM Strip mutans). Professional toothcleaning with a CHX gel was clearly most effective ( P < 0.001) but the baseline levels of streptococci returned in 11 wk. SnF 2 ‐AmF gel also reduced significantly ( P < 0.001) mutans streptococci but recolonization occurred already in 7 wk. Placebo gel, i.e. professional toothcleaning as such, did not show any statistically significant effect on the numbers of salivary mutans streptococci. None of the treatments affected the levels of lactobacilli or the total aerobic flora in saliva samples. Professional toothcleaning with a CHX gel, or with a SnF 2 ,‐AmF gel, can be regarded as an alternative to the commonly used, but more patience demanding, application of gel in mouth trays at home for individuals with high caries activity.