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Craniofacial growth in bone marrow transplant recipients treated with growth hormone after total body irradiation
Author(s) -
DAHLLÖF GÖRAN,
FORSBERG CARLMAGNUS,
NÄSMAN MARGARETA,
MATTSSON TORSTEN,
MODÉER THOMAS,
BORGSTRÖM BIRGIT,
BOLME PER,
RINGDÉN OLLE
Publication year - 1991
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1991.tb01021.x
Subject(s) - medicine , craniofacial , growth hormone , condyle , cephalometry , transplantation , radiography , bone marrow transplantation , total body irradiation , hormone , dentistry , endocrinology , orthodontics , surgery , chemotherapy , cyclophosphamide , psychiatry
— The effect of growth hormone (GH) treatment on craniofacial development was studied in five children exhibiting growth retardation following bone marrow transplantation. Linear and angular measurements were made on lateral radiographic cephalograms taken prior to the start of GH treatment and after an average treatment time of 1.2 yr. The results showed that the mean growth increments of mandibular length in the GH treated children, exceeded the corresponding values of the control group by 150% during the period of investigation. It is suggested that this dimensional increase in the patients was due to GH stimulation on the chondral growth process in the mandibular condyles.