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Immunogenic potential of some mercury compounds in experimental contact allergy of the rat oral mucosa
Author(s) -
KINNBY BERTIL,
KÖNSBERG RICHARD,
LARSSON AKE
Publication year - 1988
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1988.tb01409.x
Subject(s) - contact allergy , mercury (programming language) , oral mucosa , allergy , dermatology , medicine , dentistry , immunology , contact dermatitis , pathology , computer science , programming language
— The contact allergenic potential of substances included in a “dental screening test” has been investigated in a previously established animal model for producing contact allergy. We were unable to produce contact hypersensitivity with any of the original formulas. HgCl 2 was selected for further studies and, in order to improve its penetration, butanol was used as a solvent. Sensitization was, however, not obtained with any of the HgCl 2 /butanol formulas. Our results are discussed in relation to the requirements of reaching immunogenic threshold levels of mercury in the tissue.