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Malignant transformation in oral leukoplakia
Author(s) -
LIND PETTER O.
Publication year - 1987
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1987.tb01959.x
Subject(s) - medicine , leukoplakia , incidence (geometry) , oral leukoplakia , dysplasia , etiology , malignant transformation , dermatology , epithelial dysplasia , carcinoma , cancer , gastroenterology , pathology , physics , optics
– A retrospective study on the incidence of malignant transformation in oral leukoplakia was performed covering the period from 1970 to 1980. Carcinoma developed in 11 of the 157 patients, and this 7% incidence increased to 8.9% when the same patients were followed prospectively for 6 more years. Dysplasia was fotind in biopsies from 51 patients (31.8%), and was significantly more frequent in women than men ( P <0.05). Dysplasia grade and cancer development were related to updated clinical and etiological parameters.