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Salivary IgA, lysozyme and β‐microglobulin in periodontal disease
Author(s) -
MARKKANEN HELENA,
SYRJÄNEN STINA M.,
ALAKUIJALA PEKKA
Publication year - 1986
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1986.tb01374.x
Subject(s) - lysozyme , saliva , periodontitis , beta 2 microglobulin , medicine , chemistry , immunology , gastroenterology , biochemistry
— The concentrations of IgA, lysozyme and β‐microglobulin (β 2 ‐m) were quantitated in wax‐stimulated mixed saliva from 28 patients with severe periodontitis and from 28 healthy controls. The mutual correlations between IgA, lysozyme and β 2 ‐rn were determined. In patients with periodontitis decreased lysozyme concentrations were detected when compared with controls (P<0.05). The correlation between IgA and β 2 ‐m concentrations was highly significant in both groups studied (P<0.0001, and P <0.002), whereas β 2 ‐m and lysozyme concentrations were positively correlated in patients but not in controls. In addition, a significant correlation between IgA and lysozyme was found only in periodontal patients ( P <0.001).