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Subgingival microorganisms and bacterial virulence factors in periodontitis
Author(s) -
SLOTS JÖRGEN,
DAHLÉN GUNNAR
Publication year - 1985
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1985.tb01319.x
Subject(s) - virulence , actinobacillus , microbiology and biotechnology , virulence factor , porphyromonas gingivalis , periodontal disease , periodontitis , biology , microorganism , pathogenic bacteria , bacteria , gene , medicine , dentistry , genetics
– Considerable information has come forth in recent years on the pathogenic organisms in human periodontilis and the sequence of events by which they produce periodontal disease. Important pcriodontopatliogens include Bactcroidcs gingivalis, Bactcroidcs intcnnedius and Actinobacillus actinomycetemcomitans. Virulence factors of B. gingivalis and B. intermcdius may mainly involve enzymes with potential to interfere with host defenses and to disintegrate periodontal tissues. Pathogenic properties of A. actinomycetemcomitans appear predominantly to be exerted by leukotoxin and other noxious products.