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Rate of viscosity changes in five salivary protein fractions following pH alterations
Author(s) -
NORDBÖ HÅKON,
DARWISH SAMIA,
BHATNAGAR RAJENDRA SAHAI
Publication year - 1984
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1984.tb00895.x
Subject(s) - chemistry , viscosity , folding (dsp implementation) , proline , biophysics , saliva , conformational change , intrinsic viscosity , shock (circulatory) , biochemistry , chromatography , crystallography , medicine , organic chemistry , thermodynamics , biology , amino acid , physics , electrical engineering , engineering , polymer
– The change of viscosity with time following alteration of pH was studied in five protein fractions isolated from human parotid saliva. The results indicate that sudden pH changes may cause rapid charge alterations leading to shock‐like expansion or compression of the molecules. This quick reaction seems to be followed by more slowly proceeding conformational alterations probably involving folding, intermingling, and other types of chain interactions. The content of proline residues may influence the rate and extent of such conformational changes.