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Adsorption of glucosyltransferase to saliva coated hydroxyapatite Possible mechanism for sucrose dependent bacterial colonization of teeth
Author(s) -
RÖLLA GUNNAR,
CIARDI JOSEPH E.,
SCHULTZ SANDRA A.
Publication year - 1983
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1983.tb00786.x
Subject(s) - glucosyltransferase , saliva , adsorption , chemistry , in vitro , tooth surface , microbiology and biotechnology , salivary proteins , biofilm , sucrose , biochemistry , bacteria , enzyme , dentistry , biology , medicine , genetics , organic chemistry
– Glucosyltransferase (GTF) adsorbed to hydroxyapatite and to saliva coated hydroxyapatite in vitro. Several proteins which are known to be present in the “pellicle” which forms on hydroxyapatite when this mineral is exposed to whole saliva were shown to stimulate or inhibit GTF. It is suggested that these proteins may interact with GTF and cause binding of the enzyme to saliva coated hydroxyapatite. A model is suggested where GTF adsorbed to tooth surfaces may induce binding of microorganisms to tooth surfaces.