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Histochemical and biochemical study of here‐ditary fibrous hyperplasia of the gingiva
Author(s) -
COLLAN YRJÖ,
RANTA HELENA,
VARTIO TAPIO,
PERHEENTUPA JAAKKO,
RAESTE ANNAMAIJA
Publication year - 1982
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1982.tb01520.x
Subject(s) - connective tissue , staining , pathology , hyperplasia , chemistry , positive staining , fibroblast , anatomy , biology , medicine , in vitro , biochemistry
– Four patients with herediatry hyperplasia of the gingiva were studies. Bipsy samples of gingival tissue contained subepithelial loose connective tissue with thick rounded fibroblasts or dense collagen‐rich connective tissue with thin fibroblasts, which appeared to be inactive These two types of fibroblasts differed in electron microscopy. alcian blue‐staining of intercellular material in various. MgCL 2 concentrations was similar in hyperplastic and control samples. Collagen from the hyperplatic gngiva appeared to be more mature than normal, based onthe presence of stable, nonreducible cross lines. an investigation of growth harmone secretion and treatment trial suggested that the growth retardation observed in earlier studies was due to normal variation in growth rates (in one patient) to hypopituitarism associated with birth in breeth presentation.