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Distribution and forms of iodine in human oral cavity
Author(s) -
TENOVUO JORMA,
SÖDERLING EVA,
ANTTONEN TYTI
Publication year - 1980
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1980.tb01249.x
Subject(s) - saliva , chemistry , iodine , thiocyanate , sonication , salivary proteins , hydrolysis , in vitro , chromatography , in vivo , halogenation , tyrosine , acid hydrolysis , biochemistry , peroxidase , organic chemistry , enzyme , biology , microbiology and biotechnology
– Neither iodinated proteins nor iodinated. low‐molecular weight compounds (e.g. iodinated tyrosine derivatives) could be detected in concentrated human salivary supernatant by using the Ce(SO 4 ) 2 ‐method either directly or after thin‐layer chromatography. Salivary sediment contained free 1 − ions, loosely bound iodine (released with saline) and strongly bound iodine (released with sonication, detergent and acid hydrolysis). A positive correlation between salivary and crevicuiar excretion of l − from plasma was observed. Thiocyanate ions, which competitively inhibit peroxidase‐catalysed oxidation and iodination reactions and which are abundant in human saliva, possibly prevent the coupling of l − to protein in vivo although some human salivary proteins are very susceptible to iodination in vitro.