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Ultrastructural features of the epithelial‐mesenchymal interface in an ameloblastic fibro‐odontoma
Author(s) -
JOSEPHSEN KAJ,
LARSSON AKE,
FEJERSKOV OLE
Publication year - 1980
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1980.tb01199.x
Subject(s) - enamel paint , ultrastructure , enamel organ , connective tissue , matrix (chemical analysis) , basal lamina , mesenchymal stem cell , anatomy , pathology , chemistry , amelogenesis , basement membrane , materials science , ameloblast , biology , composite material , medicine
– The ultrastructural features of the epithelial‐mesenchymal interface in a case of an ameloblastic fibro‐odontoma was studied with special reference to possible signs of “inductive” processes. In most parts of the tumor, the odontogenic epithelium was separated from the connective tissue by a thick rim of a finely filamentous mesh work in which a basal lamina was occasionally observed. Mesenchymal cells were seen to touch the filamentous mesh work but no membrane bound matrix vesicles were recorded. Small areas of dentin‐like tissue were found in the juxtaepithelial connective tissue while enamel‐like areas and spherical calcified masses were encountered in epithelial islands. The organic matrix in relation to the enamel‐like tissue consisted of either tubular fibers or a fine‐granular material. It was assumed that the tubular matrix component directed the formation of long enamel‐like crystals, and that the fine‐granular matrix was degraded tubular fibers in which spherical calcified masses might arise. Spherical calcified masses could be found in separate follicles also where they were related to a fine‐fibrillar matrix or collagenous material. The cell layers forming the wall of the islands had a great resemblance to those of an enamel organ, but the findings of dentin‐free, enamel‐like areas are not compatible with the inductive theory of normal odontogenesis.