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Fluoride concentrations in saliva after single oral doses and their relation to plasma fluoride
Author(s) -
EKSTRAND JAN
Publication year - 1977
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1977.tb00525.x
Subject(s) - fluoride , saliva , chemistry , pharmacokinetics , plasma concentration , blood plasma , plasma levels , dentistry , endocrinology , medicine , biochemistry , inorganic chemistry
– The saliva and plasma fluoride (F) concentrations following intake of different doses of fluoride tablets were studied in six subjects. There was a close relationship between saliva F and plasma F and the ratio was 0.64±0.01 (s.e.). The plasma half life of F was 4—16 h. This results indicate that saliva F may be a useful substitute for blood sampling in studies concerning the pharmacokinetics of fluoride.