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Effect of oxytetracyclineand purified calcein (DCAF) on theapposition and mineralization of rat incisor dentin
Author(s) -
RASMUSSEN PER
Publication year - 1975
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1975.tb00431.x
Subject(s) - calcein , apposition , dentin , oxytetracycline , mineralization (soil science) , incisor , chemistry , dentistry , anatomy , medicine , biochemistry , membrane , antibiotics , organic chemistry , nitrogen
— Thirty male rats in groups of ten were given intraperitoneal injections of oxytetracycline and purified calcein (DCAF) every day for 10 d in order to determine whether these fluorescent hard tissue markers per se had any adverse effects on weight development and dentin apposition and mineralization. It was found that oxytetracycline and DCAF in doses of 15 mg/kg, which are the routine doses used by the author in hard tissue studies, do not seem to have any measurable influence on these parameters, while their ability to cause fluorescence is fully satisfying in dentin as well as in bone.