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Biologic tests of a methyl methacrylate composite material
Author(s) -
TRONSTAD LEIF,
SPÅNGBERG LARZ
Publication year - 1974
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1974.tb00371.x
Subject(s) - methyl methacrylate , methacrylate , in vivo , toxicity , pulp (tooth) , dentistry , composite number , in vitro , chemistry , materials science , nuclear chemistry , composite material , medicine , organic chemistry , biology , polymerization , biochemistry , polymer , microbiology and biotechnology
— The biologic compatibility of a methyl methacrylate composite material (Polycap®), a conventional methyl methacrylate resin (Sevriton®), and a composite material based on Bowen's resin (Concise®) was assessed in in vitro (cell culture) and in vivo (monkey teeth) tests. Freshly prepared Polycap caused some cell damage in the in vitro tests. Its toxicity was, however, markedly reduced after setting. In experiments with a cell‐material contact of 24 h, the toxicity of Polycap was, regardless of setting time, less than the toxicity of Sevriton and Concise. In the in vivo experiments, Sevriton had caused a severe pulp reaction in 5 out of 10 teeth after 80 d. Concise had caused a severe reaction in 2 out of 10 teeth, while in 20 teeth filled with Polycap, a slight reaction was observed in 15 and a moderate reaction in five teeth. After 90 d observation, repair had occurred in most teeth filled with Polycap, indicating that the reaction caused by the material in young healthy pulps is reversible. Thus it is recommended that Polycap is used together with a base.