Premium
Autoradiographic study of erupting teeth in rats after intracardial injection of 131 I‐fibrinogen
Author(s) -
MAGNUSSON BENGT
Publication year - 1973
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1973.tb01503.x
Subject(s) - fibrinogen , molar , tissue fluid , vascular permeability , chemistry , dentistry , anatomy , medicine , pathology
– In order to study the occurrence of accumulations of tissue fluid in the periapical areas of erupting teeth, 131 I‐fibrinogen was given intracardially to 15 rats, aged 15 or 16 d. The injected fibrinogen was demonstrated autoradiographically in areas of fluid accumulations at molars as well as incisors in several of the animals studied. Weak radioactivity was noted already after 1 h's survival. After 8 or 24 h some effusions produced a very intense blackening of the film. The periapical accumulations of fluid are thus apparently produced by local changes in vascular permeability.