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Effect of glucocorticoids on the 35 SO 4 incorporation in the rat incisor pulp
Author(s) -
LINDE ANDERS
Publication year - 1972
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1111/j.1600-0722.1972.tb00286.x
Subject(s) - glycosaminoglycan , dentinogenesis , pulp (tooth) , chemistry , chondroitin sulfate , sulfation , chondroitin , cellulose acetate , dentin , connective tissue , incisor , cortisone , chondroitin sulphate , endocrinology , medicine , biochemistry , dentistry , cellulose , odontoblast , pathology
– The effects of cortisone acetate and hydrocortisone acetate on the incorporation of 35 S‐labelled sulfate in the loose connective tissue of the rat incisor pulp have been studied. A reduction by 25 % and 50 %, respectively was found. This was interpreted as representing a decrease in the synthesis of sulfated glycosaminoglycans (mucopolysaccharides), especially the chondroitin sulfates which are the main glycosaminoglycan fraction in this tissue. The effects of glucocorticoids on the chondroitin sulfate synthesis are discussed in relation to dentinogenesis and tooth eruption.