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Immunohistochemical characterization of capsular cells in neuromuscular spindles of the neck
Author(s) -
Triantafyllou Asterios
Publication year - 2007
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.2007.00534.x
Subject(s) - basement membrane , laminin , immunohistochemistry , pathology , cd34 , type iv collagen , anatomy , biology , chemistry , microbiology and biotechnology , medicine , stem cell , extracellular matrix
Background: To identify capsular components of neuromuscular spindles in man by means of immunohistochemistry. Methods: Investigation of histologically observed neuromuscular spindles in surgical specimens with the use of markers for sheath cells and basement membranes. Results: Epithelial membrane antigen and CD34 immunoreactivities were found in the outer and inner capsular layers, respectively. S‐100 protein was not expressed in the capsules and there was more collagen type IV than laminin. Conclusions: Cells resembling perineurial cells and endoneurial fibroblasts, and basement membrane rich in collagen type IV comprise the capsules of neuromuscular spindles.