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Proliferative verrucous leukoplakia and its progression to oral carcinoma: report of three cases
Author(s) -
Morton Thomas H.,
Cabay Robert J.,
Epstein Joel B.
Publication year - 2007
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.2007.00499.x
Subject(s) - verrucous carcinoma , leukoplakia , medicine , carcinoma , dermatology , cancer , pathology , oral leukoplakia
Proliferative verrucous leukoplakia (PVL) is a distinct clinical form of oral leukoplakia defined by its progressive clinical course, changing clinical and histopathologic features, and potential to develop into cancer. PVL behaves in a more aggressive and relentless manner than the more innocuous white oral lesions that it can resemble clinically. We present three cases of PVL that progressed to carcinoma and discuss the histopathologic findings that may either hinder or assist in the diagnosis.