Premium
Acquired macroglossia due to lopinavir/ritonavir treatment
Author(s) -
Vritsali Eleni,
Kolokotronis Alexandros,
Valagouti Despina,
Miteloudis Georgios,
Zaraboukas Thomas,
Kioses Vassilios,
Antoniades Demetrios
Publication year - 2005
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.2004.00237.x
Subject(s) - macroglossia , ritonavir , lopinavir , medicine , tongue , drug , dermatology , biopsy , surgery , pharmacology , pathology , human immunodeficiency virus (hiv) , immunology , antiretroviral therapy , viral load
A HIV‐positive patient, 3 months after the treatment initiation with lopinavir‐/ritonavir (LPV/r) acquired macroglossia. The tongue biopsy revealed mature adipose tissue accumulated into submucosa. The drug was discontinued and the patient showed a significant improvement. This case is the first case in the medical literature of acquired macroglossia because of LPV/r, a drug causing changes in body fat composition.