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Primary intraosseous carcinoma of the mandible with probable origin from reduced enamel epithelium
Author(s) -
Ide Fumio,
Shimoyama Tetsuo,
Horie Norio,
Kaneko Takahiro
Publication year - 1999
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1999.tb02114.x
Subject(s) - pathology , mandible (arthropod mouthpart) , medicine , calcification , epithelium , carcinoma , enamel organ , soft tissue , enamel paint , metaplasia , basal cell , dentistry , biology , botany , ameloblast , genus
This report describes a case of primary intraosseous carcinoma (PIOC) arising de novo in the mandible. The patient was a 74‐year‐old woman and an early PIOC was found incidentally during histopathological examination of the pericoronal tissue obtained at extraction of a deeply impacted third molar. The curetted soft tissues consisted of a microinvasive, keratinizing squamous cell carcinoma with scattered foci of carcinoma cells showing calcification; stromal osseous metaplasia was also observed. After additional treatment, the patient has remained free of disease for 2 years. Since the tumor was completely enclosed in the bone, the only identifiable source of the present PIOC is the reduced enamel epithelium. Despite its rarity, this case emphasizes the importance of careful histologic examination of all apparently innocuous dental follicles that are removed surgically.