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Low prevalence of clinicopathologic and sialographic changes in salivary glands of men with Sögren's syndrome
Author(s) -
Saito Tohru,
Sato Jun,
Kondo Keiji,
Horikawa Masaaki,
Ohmori Keiichi,
Fukuda Hiroshi
Publication year - 1999
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1999.tb02046.x
Subject(s) - medicine , salivary gland , parotid gland , sialography , biopsy , epidemiology , gastroenterology , pathology
Sjögren's syndrome (SS) is uncommon in men and there are few reports that describe their clinical features. In the present study, we investigated salivary gland manifestations in men with SS and compared the results with those in women patients. This study included 12 men and 117 women with SS, and the mean stimulated parotid flow rate in men (4.1 ml/5 min, n=10) was higher than that of the women (3.1 ml/5 min, n=10). The prevalence of SS‐related sialographic findings, such as globular and punctate sialectasis, was significantly (P < 0.05) lower in men (3/11) than in women (72/117). The prevalence of grade 4 cases on labial salivary gland biopsy was also significantly (P < 0.01) lower in men (4/11) than in women (82/111). These results indicate a lower prevalence of SS‐related clinicopathologic and sialographic changes in men with SS than in women with the same condition.