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Prevalence of Candida species in AIDS patients and HIV‐free subjects in Thailand
Author(s) -
Teanpaisan R.,
Nittayananta W.
Publication year - 1998
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1998.tb02082.x
Subject(s) - serostatus , candida albicans , medicine , human immunodeficiency virus (hiv) , immunology , sida , gastroenterology , viral disease , biology , viral load , microbiology and biotechnology
Teanpaisan R, Nittayananta W: Prevalence of Candida species in AIDS patients and HIV‐free subjects in Thailand. J Oral Pathol Med 1998; 27: 4–7. © Munksgaard, 1998. The purpose of this study was to examine the prevalence of Candida species among groups of HIV‐infected and HIV‐free subjects in Thailand and to ascertain whether particular Candida species were associated with HIV infection. Oral rinse specimens were collected from 45 AIDS patients (CDC stage IV), 74 HIV‐free healthy subjects, and 42 HIV‐free patients who had clinical candidiasis. Yeasts recovered in culture were identified and quantified. The mean ages of the cohorts were 30.75 ± 8.19 years (AIDS group), 28.50 ± 7.98 (HIV‐free healthy group) and 41.83 ± 12.25 years (HIV‐free candidiasis group). Yeasts were isolated from 30/45 (66.66%, range 6.6 ± 10 2 ‐5.7 × 10 6 CFU/ml) of the AIDS group, 8/74 (10.81%, range 8.0 × 10 1 ‐3.5 × 10 4 CFU/ml) of the HIV‐free healthy group, and 24/42 (57.14%, range l.0 × 10 10 2 ‐1.1 × 10 5 CFU/ml) of the HIV‐free candidiasis group. There were statistically significant differences in the Candida colony counts between the AIDS group without oral candidiasis and the healthy group ( P =0.0078) and between the AIDS group with candidiasis and the HIV‐free, oral candidiasis group ( P = 0.0003). Candida albicans was the most common species recovered from AIDS patients (29 out of 30; 96.66%).