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Localised oral histoplasmosis lesions associated with HIV infection
Author(s) -
Warnakulasuriya K. A. A. S.,
Harrison J. D.,
Johnson N. W.,
Edwards S.,
Taylor C.,
Pozniak A. L.
Publication year - 1997
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1997.tb01240.x
Subject(s) - histoplasmosis , subclinical infection , medicine , disease , immunopathology , immunology , pathology , human immunodeficiency virus (hiv) , mycosis , dermatology , viral disease , antibody
Opportunistic fungal infections account for a significant amount of morbidity associated with HIV disease. We report here a case of localised oral histoplasmosis without evidence of disseminated disease in a patient who lacked stigmata of HIV disease at the time of initial presentation. The diagnosis is based on histology with special stains, complement fixing antibodies in serum, and culture of the organism from fresh tissues. Activation of subclinical disease following an infection in Uganda may explain the development of these exophytic oral lesions in this British resident.