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Exfoliative cheilitis (EC) in AIDS: association with Candida infection
Author(s) -
Reichart P. A.,
Weigel D.,
SchmidtWesthausen A.,
Pohle H.D.
Publication year - 1997
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1997.tb01239.x
Subject(s) - candida krusei , candida glabrata , medicine , fluconazole , candida tropicalis , dermatology , vermilion , mycosis , exfoliative cytology , pathology , antifungal , immunology , cytology , chemistry , organic chemistry
Forty‐seven of 165 patients with AIDS (28.5%) showed exfoliative cheilitis (EC), predominantly of the lower lip ( n =37). Histologically. hyphae were revealed in 23 of 47 cases 149%). In 14 of 23 specimens the histological and microbiological findings were in accordance. Smears of the vermilion border revealed Candida aibicans in half of the cases (51%); however, combinations with C. krusei. C. tropicalis and C. glabrata were also seen. Twenty of 35 patients given fluconazole either prophylactically or therapeutically showed clinical signs of oral candidiasis. Frequent moistening of the lips may result in infection of the vermilion border with Candida species: consequent desiccation of the lips will lead to scale formation and exfoliation. Smears of the vermilion border of the lower lip of 20 controls with AIDS were positive in four cases. Twenty HJV‐negative controls without EC showed negative microbiological results for Candida species. Exfoliative cheilitis may be associated with Candida infection in some cases and may be considered another variant of candidiasis in AIDS patients.