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Amyloid deposits in labial salivary glands identified by electron microscopy
Author(s) -
Delgado Wilson A.,
AranaChavez Victor E.
Publication year - 1997
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1997.tb00010.x
Subject(s) - pathology , ultrastructure , amyloidosis , electron microscope , amyloid (mycology) , basal lamina , salivary gland , stroma , microscopy , connective tissue , anatomy , transmission electron microscopy , chemistry , biology , medicine , immunohistochemistry , materials science , physics , optics , nanotechnology
Abnormal proteinaceous deposits identified by light microscopy as amyloid in labial salivary gland biopsies were studied by transmission electron microscopy in order to establish (heir ultrastructural characteristics. Results showed fine fibrils approximately 10 nm in diameter located in close relation to the basal lamina of the secretory end‐pieces and ducts as well as in the interstitial connective tissue stroma of labial salivary glands: these are the typical features of amyloid. Thus, the present study confirms the light microscopy diagnosis of amyloid deposits in labial salivary gland biopsies, supporting the use of lip biopsy as a readily accessible method for the diagnosis of secondary amyloidosis.