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Application of dual parameter analysis in flow cytometric DMA measurements of paraffin‐embedded samples
Author(s) -
Nylander K.,
Stenling R.,
Gustafsson H.,
Roos G.
Publication year - 1994
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1994.tb01111.x
Subject(s) - dual (grammatical number) , flow cytometry , pathology , biomedical engineering , medicine , immunology , literature , art
In a comparison of flow cytometric DNA measurements on fresh and para (Tin‐embedded material from primary squamous cell carcinomas of the head and neck region, we discovered that previously undetected aneuploid clones could he detected by dual parameter analysis of cytokeratin and DNA applied to disintegrated cells from paraffin sections. Using this new approach the correlation coefficient between DNA‐indices from fresh and paraffin‐embedded material increased from 0.42.1 to 0.904.