Premium
Paracoccidioidomycosis manifesting as oral lesions: clinical, cytological and serological investigation
Author(s) -
Sposto Maria Regina,
MendesGiannini Maria Jose,
Moraes Rosangela Aparecida,
Branco Fernanda Cristina,
Scully Crispian
Publication year - 1994
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1994.tb00262.x
Subject(s) - paracoccidioidomycosis , serology , medicine , pathology , dermatology , immunology , antibody
Paracoccidioidomycosis (South American blastomycosis) is a systemic mycosis which can he associated with oral lesions. This study on a group of 14 patients showed oral lesions mainly on the gingival or alveolar mucosa with pulmonary involvement detectable on chest radiography in most. Microscopic detection of the fungus on a direct smear showed positive results in all 14 patients. Serological investigations including immunodiffusion, counterimmunoelectrophoresis and immunoblot were also positive in 100% of cases. The results suggest that direct smear together with serology may obviate the need for lesional biopsy for the diagnosis of oral Paracoccidioidomycosis.