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Oncogenes, tumour suppressors and viruses in oral squamous carcinoma
Author(s) -
Scully Crispian
Publication year - 1993
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1993.tb01086.x
Subject(s) - basal cell , pathogenesis , carcinogen , biology , gene , cancer research , carcinoma , immunology , oncovirus , suppressor , virus , virology , medicine , pathology , genetics
The pathogenesis of oral squamous cell carcinoma involves recognised carcinogens in tobacco and/or alcohol but other factors, including viruses, may also have a role. This paper reviews the gene changes revealed in oral carcinoma, the evidence implicating viruses, and mechanisms whereby viruses may affect gene function.