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Differentiation of sugar assimilation characteristics and colony phenotypes in pathogenic and commensal oral candidal isolates
Author(s) -
Hellstein J. H.,
Fotos P. G.,
Law S. S.,
Kovacevic M.,
Carriere K. C.
Publication year - 1993
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1993.tb01080.x
Subject(s) - phenotype , biology , microbiology and biotechnology , assimilation (phonology) , phenotypic switching , sugar , colony morphology , gene , bacteria , genetics , food science , linguistics , philosophy
A comparison of sugar assimilation patterns has been made using 72 oral candidal isolates recovered from diseased and non‐diseased patients. Significant differences were demonstrated between isolates recovered from diseased versus healthy mouths. In addition, significant changes in colony phenotype (switch frequency and morphologic predominance) were found to relate to predictive data generated from carbon source utilization data. These results suggest that biochemical properties and colony phenotypic characteristics may hold promise in predicting the behavior of oral candidal isolates in disease.