Premium
Role of thermal trauma in experimental oral mucosal Candida infections in rats
Author(s) -
O'Grady John F.,
Reade Peter C.
Publication year - 1993
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1993.tb01044.x
Subject(s) - candida albicans , tongue , medicine , dorsum , etiology , corpus albicans , mycosis , oral mucosa , pathology , microbiology and biotechnology , immunology , biology , anatomy
A model of candidosis in experimental rats was used to study the role of trauma in the aetiology of oral mucosal infections caused by Candida albicans. Standardised thermal trauma was delivered to the dorsum of the tongue of Sprague‐Dawley rats and experimental candidosis was induced. Histologically. the site of trauma was invaded by hyphae earlier and more extensively than in control animals, leading to the conclusion that trauma facilitated the establishment of the C. alhicana infections.