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Detection of human papillomavirus DNA in an ameloblastoma using the in situ hybridization technique
Author(s) -
Heerden W. F. P.,
Rensburg E. J.,
Raubenheimer E. J.,
Venter E. H.
Publication year - 1993
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1993.tb01039.x
Subject(s) - in situ hybridization , human papillomavirus , ameloblastoma , in situ , dna–dna hybridization , papillomaviridae , pathology , medicine , biology , dna , genetics , cancer , dentistry , chemistry , gene , cervical cancer , maxilla , gene expression , organic chemistry
HPV type 18 DNA was identified in an intrabony ameloblastoma using radio‐labelled in situ hybridization. The viral DNA was found in a verrucous lesion in a cystic area of the tumor. The absence of HPV DNA in other epithelial areas of the ameloblastoma is suggestive of a secondary infection. HPV is not considered to be an etiological factor in the pathogenesis of this ameloblastoma.