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Giant cell lesions of the jaws: evaluation of nucleolar organizer regions in lesions of varying behavior
Author(s) -
Whitaker S. B.,
Vigneswaran N.,
Budnick S. D.,
Waldron C. A.
Publication year - 1993
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1993.tb00130.x
Subject(s) - pathology , nucleolus organizer region , giant cell , multinucleate , peripheral blood mononuclear cell , population , medicine , staining , biology , nucleolus , biochemistry , environmental health , nucleus , psychiatry , in vitro
To examine whether giant cell lesions of the jaws (GCL) of varying behavior could be separated histologically, a number of GCL were studied using the AgNOR staining technique for nucleolar organizer regions. The mean AgNOR count of mononuclear cells from recurrent lesions (1.73 ± 0.15) was slightly higher than that of the aggressive lesions (1.54 ± 0.21) and much higher than that of the non‐aggressive/non‐recurrent lesions (1.33 ± 0.14). Similarly, the mean AgNOR count of the multinucleate giant cells of the recurrent lesions (1.52 ± 0.14) was slightly higher than that of aggressive lesions (1.34 ± 0.092) and much higher than that of non‐aggressive/non‐recurrent lesions (1.26 ± 0.05). Statistical analysis showed a significant difference between the mean number of AgNORS of recurrent lesions and non‐recurrent/non‐aggressive ones in both the mononuclear and multinuclear population (p<0.05).