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Comparison between new saliva stimulants in patients with dry mouth: a placebo‐controlled double‐blind crossover study
Author(s) -
Aagaard A.,
Godiksen S.,
Teglers P. T.,
Schiodt M.,
Glenert U.
Publication year - 1992
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1992.tb01369.x
Subject(s) - placebo , saliva , crossover study , mucin , medicine , dry mouth , chewing gum , gastroenterology , double blind , dentistry , food science , pathology , chemistry , alternative medicine
Two new saliva stimulants: V6 and a mucin containing chewing gum were tested in this placebo‐controlled double‐blind crossover study. Forty‐three patients (mean age 63 yr) complaining of dry mouth participated. The products were administered in a randomized order, and used for 2 wk each. The effect was evaluated by interviews and by determining changes in stimulated and unstimulated saliva flow rates. A positive effect was reported by 64%, 44%, and 26% of the patients using the mucin chewing gum, V6, and the placebo, respectively. More than 2/3 of the patients found the mucin chewing gum efficient at various times and situations. Sixty‐one percent of the patients preferred the mucin chewing gum, 21% V6, and 5% the placebo product. Fifty percent of the patients had an increase in unstimulated salivary secretion rate from all products after 14 days regular use indicating a long‐term effect.