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Major recurrent oral ulcers in AIDS: report of three cases
Author(s) -
ReyesTerán Gustavo,
RamírezAmador Velia,
Rosa Estela,
GonzálezGuevara Martha,
León Samuel Ponce
Publication year - 1992
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1992.tb01029.x
Subject(s) - medicine , odynophagia , prednisone , dermatology , oral cavity , surgery , dysphagia , orthodontics
We report the cases of three AIDS patients who developed major recurrent oral ulcers with severe odynophagia and weight loss. The patients were treated successfully with systemic steroids. Within the first week of prednisone therapy (40 mg/day), the symptoms improved and the lesions entirely healed. We suggest, on the bases of recent literature, that superantigens and the cytokine network could be involved and they should be considered in the immunopathogenic mechanisms of this type of ulcers.