Premium
Morphometric study of nucleolar organizer regions in human oral normal mucosa, papilloma and squamous cell carcinoma
Author(s) -
Cabrini R. L.,
Schwint A. E.,
Mendez A.,
Femopase F.,
Lanfranchi H.,
Itoiz M. E.
Publication year - 1992
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1992.tb01010.x
Subject(s) - papilloma , epithelium , oral mucosa , pathology , basal cell , biology , carcinoma , nucleolus organizer region , cell , medicine , nucleolus , microbiology and biotechnology , genetics , cytoplasm
A morphometric study of nucleolar organizer regions (NOR) was performed to analyze their distribution, volume, number and shape in the different strata of human normal oral mucosa epithelium and papilloma and in squamous cell carcinoma employing microphotographs of silver‐stained paraffin sections. The different NOR‐related parameters evidenced significant differences between normal mucosa, papilloma and squamous cell carcinoma. The functional polarity of normal mucosa epithelium and of papilloma is also evidenced in terms of NOR‐related parameters. The discriminative value of certain NOR parameters was demonstrated.