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Recurrent aphthous ulceration: vitamin B1, B2 and B6 status and response to replacement therapy
Author(s) -
Nolan A.,
McIntosh W. B.,
Allam B. F.,
Lamey P.J.
Publication year - 1991
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1991.tb00950.x
Subject(s) - medicine , pyridoxine , riboflavin , thiamine , vitamin b6 , gastroenterology , vitamin , b vitamins , surgery , biochemistry , chemistry
An evaluation of the thiamine, riboflavin and pyridoxine (vitamin B1, B2 and B6) status of 60 patients with recurrent mouth ulcers was performed. Seventeen patients (28.2%) were found to be deficient in one or more of these vitamins. Replacement therapy of these vitamins was given to a study group of deficient patients and a non‐deficient group for one month. At the end of therapy and after a follow‐up period of 3 months, only those patients who had a B complex deficiency had a significant sustained clinical improvement in their mouth ulcers. Vitamin B1, B2 and B6 deficiencies should, therefore, be considered as another possible precipitating factor in recurrent aphthous ulceration.