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Immunohistochemical study of four histologic types of parotid gland pleomorphic adenoma
Author(s) -
Aroni K.,
Fotiou G.,
Liossi A.,
Bazopoulou E.,
Kyrkou K.
Publication year - 1991
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1991.tb00885.x
Subject(s) - histogenesis , immunohistochemistry , pathology , pleomorphic adenoma , parotid gland , salivary gland , adenoma , lactoferrin , biology , medicine , anatomy , genetics
The immunohistochemical detection of lysozyme, lactoferrin, a 1 ‐antiohytnotrypsin and a 1 ‐antitrypsin was used to investigate the marker expression and histogenesis of each one of four histologic types of 20 parotid gland pleomorphic adenomas. Moreover, 10 adult and 20 neonate parotid glands were studied. The immunohistochemical analysis revealed that tumor types 1 and 2 are nearly identical immunohistochemically while types 3 and 4 differ from one another, as well as from types 1 and 2. The markers used failed to suggest that the tumor arises from epithelial cells of any specific anatomic part of the parotid gland.