Premium
Recurrent aphthous ulceration and food sensitivity
Author(s) -
Nolan A.,
Lamey PJ.,
Milligan K. A.,
Forsyth A.
Publication year - 1991
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1991.tb00406.x
Subject(s) - medicine , dermatology , allergy , food allergy , oral submucous fibrosis , allergen , gastroenterology , surgery , immunology
Forty patients with recurrent aphthous ulceration (RAU) were investigated to ascertain the possibility of food sensitivity being a significant precipitating factor in their recurrent oral ulceration. All patients were hematologically normal and did not respond to vitamin Bl and B6 therapy. Patch testing (Standard European Series) was undertaken in 21 patients. Twenty patients showed a positive reaction to a number of substances which were considered clinically relevant. Professional advice on avoidance of the allergen was given, resulting in an improvement in eighteen patients. It is concluded that food sensitivity and allergies to other substances should be considered as an etiologic factor in hematologically normal patients with recurrent oral ulceration.