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A variant of calcifying epithelial odontogenic tumor with Langerhans cells
Author(s) -
Asano Masatake,
Takahashi Tomihisa,
Kusama Kaoru,
Iwase Takashi,
Hori Minoru,
Yamanoi Hiromitsu,
Tanaka Hiroshi,
Moro Itaru
Publication year - 1990
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1990.tb00874.x
Subject(s) - birbeck granules , pathology , eosinophilic , keratin , homogeneous , langerhans cell , biology , calcification , cytoplasm , microbiology and biotechnology , antigen , medicine , immunology , physics , thermodynamics
A variant of calcifying epithelial odontogenic tumor (CEOT) with Langerhans cells is reported. Compared to a typical CEOT, the tumor islands of this case were thin and composed of a small number of polyhedral epithelial cells. Almost no calcification of homogenous eosinophilic materials was observed. In addition, clear cells which structurally corresponded to Langerhans cell were intermingled in the epithelial islands. These cells stain positively for S‐100 protein, lysozome, MT 1, LN‐3 and OKT 6 antibodies, but not for keratin antibody. Electronmicroscopic examination revealed the rod‐shaped and racket‐shaped structures called Birbeck's granules in the cytoplasm of these clear cells. Our observations indicate a variant case of CEOT with Langerhans cells in tumor nests.